This PedsCases Note provides a one-page infographic on Mononucleosis. Mononucleosis, commonly known as mono or the “kissing disease,” is most often caused by the Epstein-Barr virus (EBV. It was created by Melanie Ratnayake (Medical Student, University of Toronto) and Dr. Kescha Kazmi (Paediatric Infectious Diseases Staff, SickKids/University of Toronto)

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An author of this Note has financial support from Bavarian Nordic 

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References: 

• Luzuriaga K, Sullivan JL. (2010). Infectious mononucleosis. New England Journal of Medicine, 362(21), 1993–2000. https://doi.org/10.1056/NEJMcp1001116
• Ebell MH. (2004). Epstein–Barr virus infectious mononucleosis. American Family Physician, 70(7), 1279–1287.
• Centers for Disease Control and Prevention. (2024). Epstein–Barr Virus and Infectious Mononucleosis. https://www.cdc.gov/epstein-barr/
• Kimberlin DW, Barnett ED, Lynfield R, Sawyer MH, eds. (2024). Red Book: 2024 Report of the Committee on Infectious Diseases (33rd ed.). American Academy of Pediatrics.
• Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. (2023). Nelson Textbook of Pediatrics (22nd ed.). Elsevier.
• Public Health Ontario. (2023). Epstein–Barr Virus – Laboratory Testing. https://www.publichealthontario.ca